Books

Gregor Mendel, a monk at the St. Thomas Monastery in what is now the Czech Republic, is widely considered the father of modern-day genetics. His pioneering analysis of inheritance in peas is probably familiar to every student who has studied biology. But his path to greatness wasn’t an easy one. As a young monk, he was unable to pass an examination that was required to certify him as a grade school science teacher. Despite his failure, the committee administering the exam felt that he showed some promise and he was sent to the University of Vienna to make up for his deficiencies. After two years of study, he sat again for the test. But this time, he walked out without even handing in his paper. No one knows why. It’s a mystery for which I offer a wholly fictitious and romantic explanation.

This book describes the foundations underlying the latest exciting developments in cancer immunotherapy. It’s not meant to be a source for medical advice. Rather it is intended to explain the science behind many of the most recent therapies that are being offered to cancer sufferers, and to point patients and practitioners to possible future developments. About half of the book provides an introduction to the immune system, a third to the biology of oncogenesis, the remainder to the application of immunology to the conquest of cancer. While the book spans over 45 chapters, Individual chapters are purposely bite sized and there are many illustrations. A college course in general biology should be preparation enough to follow along. However, for those in need of more background, there is an appendix that provides a short review of basic molecular biology.

This book represents my attempt to convey the excitement of cloning and stem cell research to a wide audience while building on a foundation that starts from basic principles. I have tried to write a book that starts from more or less ground zero and works its way up to current advances. I’ve also attempted to keep jargon to a minimum so that readers aren’t always turning to a dictionary to look up definitions. While writing the book, I found that I also had to confront some nonscientific matters. While the new cell biology has incredible promise – biologists are developing tools to offer some extraordinarily useful therapies – some in the public are wary of its power. They fear a slippery slope. They claim that the scientific community is “playing God”. They bring up deep ethical and moral issues and pose profound questions like “When does life begin?”. While they’re not a major focus of the book, I have tried to address some of the major controversies with as little prejudice as I can muster.

This book focuses less on the facts of molecular genetics and more on the process of discovery. Who made the major advances? How did they come to the breakthroughs that they achieved? What was their educational experience? Who were their lesser-known colleagues and collaborators and who were their major adversaries? Did the scientific community fully appreciate the significance of their findings? Did they get the credit they deserved? What was the intellectual climate like in their time? What obstacles did they have to overcome? This book tries to answer these questions with respect to a few of the major contributors to the science of genetics.

Out of print. Out of date.

Death Delivered

Published with Amazon, October 2023,

A semi-autobiographical novel, it’s intended to be a humorous murder mystery.

Implant

In preparation, 2023. Tentative title

A science fiction novel set in the near future. Expected publication, fall 2023.

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